Ethanolamine → HCID 178510345, compound

Participants

Reaction Steps

58 mg (0.124 mmol) of 2-chloro-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)-4-(1H-pyrazol-3-yl)pyridine-3,5-dicarbonitrile were dissolved in 1 ml of tetrahydrofuran, and 15 mg (0.247 mmol) of 2-aminoethanol were added. After 30 minutes of stirring, methanol was added, the mixture was filtered and the filtrate was purified by preparative HPLC. This gave 63 mg (100% of theory) of the target compound.

Provenance & Evidence