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HRID1969936

反应详情

EQUATION

反应方程式

HRID 1969936 的结构方程式

REACTANTS

反应物

2
结构：Cc1cccc(N)c1
HCID7934

3-Methylaniline

C7H9N

结构：O=C(O)c1c[nH]c2c(=O)[nH]c3ccc(S(=O)(=O)Cl)cc3c12
HCID45121068

未命名化合物

PRODUCTS

生成物

1
结构：CCC(=O)[O-].Cc1cccc(NS(=O)(=O)c2ccc3[nH]c(=O)c4[nH]ccc4c3c2)c1
HCID86627462

未命名化合物

收率 45.9%

PROCEDURE

实验过程

This compound is prepared according to synthesis 25, from 150 mg (0.46 mmol) of 8-chlorosulfonyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 2) and 59 μL (0.55 mmol) of 3-methylaniline. After purification by chromatography on silica (eluent dichloromethane/methanol 96/4) then trituration in diethyl ether, 45 mg (23%) of 4-oxo-8-m-tolylsulfamoyl-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate is obtained in the form of a white solid.

WORKUP

后处理

  1. customThis compound is prepared
  2. customAfter purification by chromatography on silica (eluent dichloromethane/methanol 96/4)