Indoline → HCID 86627478, compound

Participants

Reaction Steps

This compound is prepared according to synthesis 25, from 150 mg (0.46 mmol) of 8-chlorosulfonyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 2) and 62 μL (0.55 mmol) of 2,3-dihydro-1H-indole. After purification by chromatography on silica (eluent dichloromethane/methanol 96/4) then trituration in methanol, 40 mg (20%) of 8-(2,3-dihydro-indole-1-sulfonyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate is obtained in the form of a white solid.

Provenance & Evidence