Triethylamine → HCID 86627482, compound

Participants

Reaction Steps

This compound is prepared according to synthesis 25, from 115 mg (0.35 mmol) of 8-chlorosulfonyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 2), 147 μL (1.05 mmol) of triethylamine and 35 mg (0.42 mmol) of dimethylamine hydrochloride. After purification by chromatography on silica (eluent dichloromethane/methanol 95/5) then trituration in methanol, 30 mg (24%) of 8-dimethylsulfamoyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate is obtained in the form of a white solid.

Provenance & Evidence