Triethylamine → HCID 86627485, compound

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Reaction Steps

This compound is prepared according to synthesis 25, from 115 mg (0.35 mmol) of 8-chlorosulfonyl-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 2), 147 μL (1.05 mmol) of triethylamine and 59 mg (0.42 mmol) of methyl 3-aminopropanoate hydrochloride. After purification by chromatography on silica (eluent dichloromethane/methanol 96/4), 25 mg (18%) of 8-(2-ethoxycarbonyl-ethylsulfamoyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate is obtained in the form of a gray solid.

Provenance & Evidence