4-t-Butylbenzenesulfonyl chloride → HCID 86627498, compound

Participants

Reaction Steps

This compound is prepared according to synthesis 43, from 60 mg (0.20 mmol) of 8-amino-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate hydrochloride (synthesis 64) and 55 mg (0.23 mmol) of 4-tert-butyl-benzenesulfonyl chloride. After recrystallization from acetonitrile/dichloromethane mixture, 36 mg (40%) of 8-(4-tert-butyl-benzenesulfonylamino)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate is obtained in the form of a light brown solid.

Provenance & Evidence