HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1,3-propanediamine → N-(3-dimethylamino-propyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Reactant | 4-oxo-3H,4H,5H-pyrrolo[2,3-c]quinoline-1-carboxylic acid | HCID 12065084 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-(3-dimethylamino-propyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxamide | HCID 15605163 | 36% |
Reaction Steps
This compound is prepared according to synthesis 79 from 75 mg (0.33 mmol) of 4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 75) and 46 μL (0.36 mmol) of 3-dimethylaminopropylamine. After trituration in diethyl ether, 37 mg (36%) of N-(3-dimethylamino-propyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxamide is obtained in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426437B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-224faa4d5b4c4d0cb12a7df6430a0948 |
| Source note | uspto-grants-2013_04 |