4-Pyridinemethanamine → N-(pyridin-4-ylmethyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxamide

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Reaction Steps

This compound is prepared according to synthesis 79 from 75 mg (0.33 mmol) of 4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxylic acid (synthesis 75) and 37 μL (0.36 mmol) of pyridin-4-ylmethylamine. The precipitate that forms during the reaction is filtered then washed with dimethylformamide and diethyl ether to give 46 mg (44%) of N-(pyridin-4-ylmethyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-carboxamide in the form of a white solid.

Provenance & Evidence