反应详情

10 mg of palladium on charcoal is added to a suspension of 14 mg (0.04 mmol) of 4-oxo-8-phenylethynyl-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate in 5 ml of ethanol and the mixture is placed under a hydrogen atmosphere for 24 hours. The raw reaction product is then filtered on celite, and the filtrate is evaporated. The residue is triturated with methanol to give 4 mg (28%) of 4-oxo-8-phenethyl-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate in the form of a white solid.

1. customThe raw reaction product
2. filtrationis then filtered on celite
3. customthe filtrate is evaporated
4. customThe residue is triturated with methanol