Trifluoroacetic acid → HCID 68934732, compound

Participants

Reaction Steps

0.5 mL of trifluoroacetic acid is added to a solution of 120 mg (0.22 mmol) of 8-(3-tert-butoxycarbonylaminophenyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate dissolved in 2 mL of dichloroethane. The solution is stirred at room temperature for 30 minutes then the solvents are evaporated. The residue is triturated with diisopropyl ether then the solid is filtered and washed with dichloromethane to give 86 mg (69%) of 8-(3-aminophenyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate trifluoroacetate in the form of a beige solid.

Provenance & Evidence