4-(Methanesulfonyl)phenylboronic acid → 8-(4-Methanesulfonyl-phenyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline 1-ethyl carboxylate

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Reaction Steps

This compound is prepared according to synthesis 229, from 200 mg (0.49 mmol) of 8-bromo-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate and 110 mg (0.55 mmol) of 4-methanesulfonylphenylboronic acid to give, after purification by chromatography on silica (eluent dichloromethane/methanol 95/5), 49 mg (32%) of 8-(4-methanesulfonyl-phenyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate in the form of a white solid.

Provenance & Evidence