4-Cyanophenylboronic acid → HCID 131730527, compound

Participants

Reaction Steps

This compound is prepared according to synthesis 229, from 200 mg (0.49 mmol) of 8-iodo-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate and 115 mg (0.78 mmol) of 4-cyanophenylboronic acid to give, after purification by chromatography on silica (eluent dichloromethane/methanol 98/2) then recrystallization from methanol, 11 mg (6%) of 8-(4-cyano-phenyl)-4-oxo-4,5-dihydro-3H-pyrrolo[2,3-c]quinoline-1-ethyl carboxylate in the form of a pale yellow solid.

Provenance & Evidence