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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1970120Generated: October 25, 2026

1,2-Ethanediamine, N1,N1,N2-trimethyl- → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-dimethylamino-ethyl)-methyl-amino]-thiazol-4-one

https://huagongshe.com/reaction/1970120

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Ethanediamine, N1,N1,N2-trimethyl-HCID 67338—
Reactant5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazolidin-4-oneHCID 86656523—
Product5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-dimethylamino-ethyl)-methyl-amino]-thiazol-4-oneHCID 67344613—

Reaction Steps

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-dimethylamino-ethyl)-methyl-amino]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazolidin-4-one and N,N,N′-Trimethyl-ethane-1,2-diamine following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426604B2
Source datasetuspto-grants-2013_04
ORD IDord-a8c8a679e0de49f2b2cffe90048cdda9
Source noteuspto-grants-2013_04