1-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzene → HCID 86656524, compound

HRID 1970122Notes

Reaction equation

HRID 1970122 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1.Br[CH2:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH3:23])(=[O:22])=[O:21])=[CH:16][C:15]=1[Cl:24]>>[Cl:24][C:15]1[CH:16]=[C:17]([S:20]([CH3:23])(=[O:22])=[O:21])[CH:18]=[CH:19][C:14]=1[CH2:13][N:1]1[C:9]2[C:4](=[CH:5][C:6]([CH:10]=[O:11])=[CH:7][CH:8]=2)[CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 27610831-(Bromomethyl)-2-chloro-4-(methylsulfonyl)benzeneHCID 212506441H-Indazole-5-carboxaldehyde

Product 1

HCID 86656524HCID 86656524, compound

Procedure

1-(2-Chloro-4-methanesulfonyl-benzyl)-1H-indazole-5-carbaldehyde was prepared from 1H-indazole-5-carbaldehyde and 1-Bromomethyl-2-chloro-4-methanesulfonyl-benzene following General Procedure A.

Sources & evidence

ORD record
ord-cdda64e8ee0142f49bb80232f814f3e1
Source dataset
uspto-grants-2013_04
Patent number
US08426604B2

Reaction notes

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