1H-Indazole-5-carboxaldehyde → HCID 86656525, compound

HRID 1970131Notes

Reaction equation

HRID 1970131 reaction equation
Br[CH2:2][C:3]1[C:8]([Cl:9])=[CH:7][C:6]([C:10]([F:13])([F:12])[F:11])=[CH:5][N:4]=1.[NH:14]1[C:22]2[C:17](=[CH:18][C:19]([CH:23]=[O:24])=[CH:20][CH:21]=2)[CH:16]=[N:15]1>>[Cl:9][C:8]1[C:3]([CH2:2][N:14]2[C:22]3[C:17](=[CH:18][C:19]([CH:23]=[O:24])=[CH:20][CH:21]=3)[CH:16]=[N:15]2)=[N:4][CH:5]=[C:6]([C:10]([F:13])([F:12])[F:11])[CH:7]=1

Participants

3

Reactant 2

HCID 212506441H-Indazole-5-carboxaldehydeHCID 673456082-(Bromomethyl)-3-chloro-5-(trifluoromethyl)pyridine

Product 1

HCID 86656525HCID 86656525, compound

Procedure

1-(3-Chloro-5-trifluoromethyl-pyridin-2-ylmethyl)-1H-indazole-5-carbaldehyde was prepared from 2-Bromomethyl-3-chloro-5-trifluoromethyl-pyridine and 1H-indazole-5-carbaldehyde following General Procedure A.

Sources & evidence

ORD record
ord-46942d8b682248d19f5d10c6b7b0c025
Source dataset
uspto-grants-2013_04
Patent number
US08426604B2

Reaction notes

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