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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1970143Generated: October 26, 2026

N,O-Dimethylhydroxylamine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(methoxy-methyl-amino)-thiazol-4-one

https://huagongshe.com/reaction/1970143

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
Reactant5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-oneHCID 86656522—
Product5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(methoxy-methyl-amino)-thiazol-4-oneHCID 76774444—

Reaction Steps

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(methoxy-methyl-amino)-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one and O,N-Dimethyl-hydroxylamine following General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426604B2
Source datasetuspto-grants-2013_04
ORD IDord-c60545400d8149d180e603956518db54
Source noteuspto-grants-2013_04