HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Methyl-2-(4-methylpiperazin-1-yl)ethan-1-amine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{methyl-[2-(4-methyl-piperazin-1-yl)-ethyl]-amino}-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Methyl-2-(4-methylpiperazin-1-yl)ethan-1-amine | HCID 14979290 | — |
| Reactant | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one | HCID 86656522 | — |
| Product | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{methyl-[2-(4-methyl-piperazin-1-yl)-ethyl]-amino}-thiazol-4-one | HCID 67348992 | — |
Reaction Steps
5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-{methyl-[2-(4-methyl-piperazin-1-yl)-ethyl]-amino}-thiazol-4-one one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one and methyl-[2-(4-methyl-piperazin-1-yl)-ethyl]-amine following General Procedure B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426604B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-1f29d4a6cb894c75bd96eb1ce99806ba |
| Source note | uspto-grants-2013_04 |