1,2-Ethanediamine, N1,N1-diethyl-N2-methyl- → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-diethylamino-ethyl)-methyl-amino]-thiazol-4-one

HRID 1970151Notes

Reaction equation

HRID 1970151 reaction equation
[Cl:1][C:2]1[CH:26]=[CH:25][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][CH:20](SC)[NH:19][C:18]4=[O:24])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:27]([F:30])([F:29])[F:28])[CH:3]=1.[CH2:31]([N:33]([CH2:38][CH3:39])[CH2:34][CH2:35][NH:36][CH3:37])[CH3:32]>>[Cl:1][C:2]1[CH:26]=[CH:25][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([CH:16]=[C:17]4[S:21][C:20]([N:36]([CH2:35][CH2:34][N:33]([CH2:38][CH3:39])[CH2:31][CH3:32])[CH3:37])=[N:19][C:18]4=[O:24])=[CH:13][CH:14]=3)[CH:9]=[N:8]2)=[C:4]([C:27]([F:29])([F:30])[F:28])[CH:3]=1

Participants

3

Reactant 2

HCID 660341,2-Ethanediamine, N1,N1-diethyl-N2-methyl-HCID 866565225-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one

Product 1

HCID 673456165-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-diethylamino-ethyl)-methyl-amino]-thiazol-4-one

Procedure

5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-diethylamino-ethyl)-methyl-amino]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one and N,N-Diethyl-N′-methyl-ethane-1,2-diamine following General Procedure B.

Sources & evidence

ORD record
ord-32151bd9e9904b9c9de1484742f6d580
Source dataset
uspto-grants-2013_04
Patent number
US08426604B2

Reaction notes

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