HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,1-dimethylpyrrolidin-3-amine → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-thiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,1-dimethylpyrrolidin-3-amine | HCID 2758520 | — |
| Reactant | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one | HCID 86656522 | — |
| Product | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-thiazol-4-one | HCID 67348904 | — |
Reaction Steps
5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[methyl-(1-methyl-pyrrolidin-3-yl)-amino]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazolidin-4-one and methyl-(1-methyl-pyrrolidin-3-yl)-amine following General Procedure B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426604B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-d07a622c2e09444090f3ac1115eab4a1 |
| Source note | uspto-grants-2013_04 |