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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1970161Generated: November 1, 2026

HCID 52911109, compound → HCID 86656528, compound

https://huagongshe.com/reaction/1970161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 52911109HCID 52911109—
Reactant5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 86654540—
ProductHCID 86656528HCID 86656528—

Reaction Steps

4-({5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-methyl-amino)-2-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 2-Hydroxymethyl-4-methylamino-pyrrolidine-1-carboxylic acid tert-butyl ester following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426604B2
Source datasetuspto-grants-2013_04
ORD IDord-0859ca7fdc6b4c37983e1d6e156568de
Source noteuspto-grants-2013_04