HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(Methylamino)-3-(pyrrolidin-1-yl)propan-2-ol → 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-hydroxy-3-pyrrolidin-1-yl-propyl)-methyl-amino]-thiazol-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(Methylamino)-3-(pyrrolidin-1-yl)propan-2-ol | HCID 22562028 | — |
| Edukt | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazolidin-4-one | HCID 86656530 | — |
| Produkt | 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-hydroxy-3-pyrrolidin-1-yl-propyl)-methyl-amino]-thiazol-4-one | HCID 67345604 | — |
Reaktionsschritte
5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(2-hydroxy-3-pyrrolidin-1-yl-propyl)-methyl-amino]-thiazol-4-one was prepared from 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-propylsulfanyl-thiazolidin-4-one and 1-Methylamino-3-pyrrolidin-1-yl-propan-2-ol following General Procedure B.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08426604B2 |
| Quelldatensatz | uspto-grants-2013_04 |
| ORD ID | ord-52995a6be2444183baea465e399a0450 |
| Quellennotiz | uspto-grants-2013_04 |