HRID1970173

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67345434

未命名化合物

结构：O=Cc1ccc2c(c1)c(I)nn2Cc1ccc(C(F)(F)F)cc1C(F)(F)F

HCID86654585

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCN(C)C1=NC(=O)C(=Cc2ccc3c(c2)c(I)nn3Cc2ccc(C(F)(F)F)cc2C(F)(F)F)S1

HCID86656531

未命名化合物

PROCEDURE

实验过程

5-[1-(2,4-Bis-trifluoromethyl-benzyl)-3-iodo-1H-indazol-5ylmethylene]-2-[(2-diethylamino-ethyl)-methyl-amino]-thiazol-4-one was prepared from 1-(2,4-Bis-trifluoromethyl-benzyl)-3-iodo-1H-indazole-5-carbaldehyde and 2-[(2-Diethylamino-ethyl)-methyl-amino]-thiazol-4-one following General Procedure E.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-243c52db517146bcb820deb1b55a15fb
来源数据集: uspto-grants-2013_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08426604B2
来源说明: uspto-grants-2013_04

反应 SMILES

[F:1][C:2]([F:27])([F:26])[C:3]1[CH:21]=[C:20]([C:22]([F:25])([F:24])[F:23])[CH:19]=[CH:18][C:4]=1[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([CH:15]=O)=[CH:12][CH:13]=2)[C:8]([I:17])=[N:7]1.[CH2:28]([N:30]([CH2:41][CH3:42])[CH2:31][CH2:32][N:33]([CH3:40])[C:34]1[S:35][CH2:36][C:37](=[O:39])[N:38]=1)[CH3:29]>>[F:1][C:2]([F:26])([F:27])[C:3]1[CH:21]=[C:20]([C:22]([F:24])([F:23])[F:25])[CH:19]=[CH:18][C:4]=1[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([CH:15]=[C:36]3[S:35][C:34]([N:33]([CH2:32][CH2:31][N:30]([CH2:41][CH3:42])[CH2:28][CH3:29])[CH3:40])=[N:38][C:37]3=[O:39])=[CH:12][CH:13]=2)[C:8]([I:17])=[N:7]1