HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one → HCID 67346623, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one | HCID 67240123 | — |
| Reactant | HCID 67346632 | HCID 67346632 | — |
| Product | HCID 67346623 | HCID 67346623 | — |
Reaction Steps
4-({5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-methyl-amino)-3-fluoro-piperidine-1-carboxylic acid tert-butyl ester was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 3-Fluoro-4-methylamino-piperidine-1-carboxylic acid tert-butyl ester (compound described in J. Med. Chem. 2008, 51, 4239-4252) following General Procedure C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08426604B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-b31210731932436e9add6bbff8dccb1b |
| Source note | uspto-grants-2013_04 |