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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1970187Generated: October 25, 2026

4-Methylamino-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester → HCID 67346625, compound

https://huagongshe.com/reaction/1970187

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methylamino-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 53414200—
Reactant5-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-oneHCID 67240123—
ProductHCID 67346625HCID 67346625—

Reaction Steps

4-({5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-4-oxo-4,5-dihydro-thiazol-2-yl}-methyl-amino)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester was prepared from 5-[1-(4-Chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one and 4-Methylamino-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester following General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08426604B2
Source datasetuspto-grants-2013_04
ORD IDord-5c680503d79846709eb54ec0b526a4f2
Source noteuspto-grants-2013_04