2-Chlorocyclohexanone → HCID 73799249, compound

Participants

Reaction Conditions

Reaction Steps

3.0 g (22.6 mmol) of 2-chlorocyclohexanone were initially charged in 30 ml of ethanol, and 1.9 g (22.6 mmol) of O-methyl hydroxylamine hydrochloride were added with stirring at from 20 to 25° C. This mixture was stirred for about 20 hours at from 20 to 25° C., adjusted with sat. NaHCO3 solution to a pH between 7 and 8 and extracted with ethyl acetate. After washing with sat. NaCl solution, the combined organic phases were dried and then freed from the solvent. The title compound (3.4 g) was directly used further.

Provenance & Evidence