Dimethyl Sulfoxide → 3-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-piperidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-

HRID 197038Notes

Reaction equation

HRID 197038 reaction equation
[CH3:27][O-:28].[CH3:30][S:31]([CH3:32])=[O:33].[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[c:9]([F:26])[cH:10][c:11]3[c:12](=[O:25])[c:13]([C:22](=[O:23])[OH:24])[cH:14][n:15]([CH:19]4[CH2:20][CH2:21]4)[c:16]3[c:17]2[F:18])[CH2:5][CH2:6][CH2:7]1.[Na+:29]>>[NH2:1][CH:2]1[CH2:3][N:4]([c:8]2[c:9]([F:26])[cH:10][c:11]3[c:12](=[O:25])[c:13]([C:22](=[O:23])[OH:24])[cH:14][n:15]([CH:19]4[CH2:20][CH2:21]4)[c:16]3[c:17]2[O:28][CH3:27])[CH2:5][CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 923Sodium ionHCID 3826051MethoxideHCID 14962342HCID 14962342, compound

Product 1

HCID 1480763-Quinolinecarboxylic acid, 1,4-dihydro-7-(3-amino-1-piperidinyl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-

Sources & evidence

ORD record
ord-e4ba3ccc564c43ec967dd6446fa9a36f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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