HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylamine → 2-(3-Chlorobenzyl)-4-(cyclopentylamino)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | 2-(3-Chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile | HCID 58407802 | — |
| Product | 2-(3-Chlorobenzyl)-4-(cyclopentylamino)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile | HCID 135995110 | — |
Reaction Steps
In analogy to the preparation of Example 1, 100 mg (0.34 mmol) of 2-(3-chlorobenzyl)-4-(methyl-sulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 292 mg (3.43 mmol) of cyclopentylamine to give 10 mg (9% of theory) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431573B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-06a2ce43274642f7841e18ddc7db0964 |
| Source note | uspto-grants-2013_04 |