Benzyl Alcohol → HCID 44198071, compound

HRID 1970956Notes

Reaction equation

HRID 1970956 reaction equation
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[N:9]=2)[N:5]=[C:4]([C:15]2[CH:16]=[C:17]([C:21]3[CH:26]=[CH:25][C:24]([C:27]([N:29]4[CH2:33][CH2:32][CH:31]([N:34]([CH3:36])[CH3:35])[CH2:30]4)=[O:28])=[CH:23][CH:22]=3)[CH:18]=[N:19][CH:20]=2)[CH:3]=1.[CH2:37]([OH:44])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[CH2:37]([O:44][C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[N:9]=2)[N:5]=[C:4]([C:15]2[CH:16]=[C:17]([C:21]3[CH:26]=[CH:25][C:24]([C:27]([N:29]4[CH2:33][CH2:32][CH:31]([N:34]([CH3:36])[CH3:35])[CH2:30]4)=[O:28])=[CH:23][CH:22]=3)[CH:18]=[N:19][CH:20]=2)[CH:3]=1)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 44198199HCID 44198199, compound

Product 1

HCID 44198071HCID 44198071, compound

Procedure

This compound is prepared from (4-{5-[6-chloro-2-(6-methyl-pyridin-2-yl)-pyrimidin-4-yl]-pyridin-3-yl}-phenyl)-(3-dimethylamino-pyrrolidin-1-yl)-methanone (Ex. 16) and benzyl alcohol analogously to Example 8; [M+H]+=571.

Sources & evidence

ORD record
ord-6e813c736a1446c0b3725399d5eb0576
Source dataset
uspto-grants-2013_04
Patent number
US08431578B2

Reaction notes

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