HRID1971105

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CNC(=O)[C@@H](NC(=O)c1nc(-c2ccccc2)n2c1CN(C)CC2)C(C)(C)C

HCID57635105

未命名化合物

结构：CNC(=O)[C@@H](NC(=O)c1nc(C(=O)c2ccccc2)n2c1CNCC2)C(C)(C)C

HCID57635545

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)[C@@H](NC(=O)c1nc(C(=O)c2ccccc2)n2c1CN(C)CC2)C(C)(C)C

HCID57635244

未命名化合物

PROCEDURE

实验过程

Compound 289 was synthesized in the same manner as described above for Compound 48 in Example 5 except that 25C was used in place of Compound 2. 1H-NMR (400 MHz, CD3OD) δ: 1.04 (s, 9H), 2.55 (s, 3H), 2.75 (d, 3H), 2.93 (t, 2H), 4.03 (d, 2H), 4.35 (d, 1H), 4.56 (t, 2H), 7.53 (t, 2H), 7.64 (m 1H), 7.86 (d, 1H), 8.19 (m, 1H), 8.31 (d, 2H); LCMS (+ESI) m/z 412.1 [M+H]+.