HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanesulfonyl chloride → HCID 57635209, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanesulfonyl chloride | HCID 11667 | — |
| Reactant | HCID 57635098 | HCID 57635098 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57635209 | HCID 57635209 | — |
Reaction Steps
To a solution of Compound 314 (20 mg) and TEA (15 μL) in DCM was added ethanesulfonyl chloride (10 μL). After stirring at room temperature for 1 hour, the reaction was quenched with saturated aqueous NaHCO3. The organic phase was separated and dried over anhydrous Na2SO4. Evaporation under reduced pressure gave Compound 461. LC/MS (+ESI) m/z 476.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431565B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-bab4231ac9ca4fceb52051b050c14592 |
| Source note | uspto-grants-2013_04 |