反应详情

4.20 g N-{[(4-phenyl-1,3-thiazole-2-yl)amino]carbonothioyl}benzamide (339 mmol) were suspended in 40 ml methanol, were dissolved in aqueous sodium hydroxide (550 mg NaOH dissolved in 3 ml H2O) and were heated for 3 hours at reflux. The reaction mixture was evaporation-concentrated, the residue obtained was stirred with water and the precipitated solid was suction-isolated. After drying, 2.90 g of a light yellow solid were obtained.

1. temperaturewere heated for 3 hours
2. temperatureat reflux
3. concentrationThe reaction mixture was evaporation-concentrated
4. customthe residue obtained
5. customthe precipitated solid was suction-isolated
6. customAfter drying