HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 178491354, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 178491353 | HCID 178491353 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178491354 | HCID 178491354 | — |
Reaction Steps
Acetylation of 110 mg N-(2,6-dimethoxybenzyl)-N′-(4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-yl)guanidine (0.26 mmol, Example 221.3) under standard conditions with acetylchloride and triethylamine in 15 ml THF followed by purification, yielded 16 mg of the desired product as a white solid; ESI-MS [M+H+]=390.15.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431604B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-0a3ef8069c16438c95c686ea9271505b |
| Source note | uspto-grants-2013_04 |