Hydrochloric Acid → HCID 58124924, compound

Participants

Reaction Steps

To a suspension of 110 mg of 10o in 1 ml of dioxane, was added 75 μl of anisole and 500 μl of 4N HCl in dioxane. After 1 hr the reaction mixture was diluted with 10 ml of sat. NaHCO3 and the product was extracted with ethyl acetate. The organic layer was washed once with sat. NaCl, dried and concentrated. The residue was triturated with diethyl ether, to provide 90 mg of 10q as white crystalline material. Mp: 250-252° C.; Rf 0.60 (CH2Cl2/methanol 8/2);

Provenance & Evidence