Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | HCID 58124889 | HCID 58124889 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 58124873 | HCID 58124873 | 80.2% |
Reaction Steps
A mixture of 580 mg of 14c and 1 g of anhydrous sodium acetate in 8 ml of acetic anhydride was heated at 100° C. for 45 min. The reaction mixture was cooled and 25 ml of water was added and stirring prolonged for 1 h. The product crystallized from the reaction mixture and was filtered, washed with water and dried in vacuo, to give 420 mg of 14d as white crystalline material; Mp 205-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08431564B2 |
|---|
| Source dataset | uspto-grants-2013_04 |
|---|
| ORD ID | ord-aaff33feec1445cabdf1ba1b8f317195 |
|---|
| Source note | uspto-grants-2013_04 |
|---|
