Hydrochloric Acid → HCID 58124854, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 180 mg of 17e in 2 ml of dioxane was mixed with a solution of 120 mg of KOH in 1 ml of water. The mixture was stirred for 1 hr at 50° C. The reaction mixture was cooled and diluted with 10 ml of water, acidified to pH 3 with 1N HCl and the product was extracted into ethyl acetate. The organic extract was washed twice with water, dried and concentrated, to provide 175 mg of 17f as a colorless oil.

Provenance & Evidence