HCID 50939112, compound → HCID 58124951, compound

HRID 1971740Notes

Reaction equation

HRID 1971740 reaction equation
[C:1]([N:5]1[CH2:40][CH2:39][CH2:38][CH2:37][C:8]2[C:9]([C:32]3[S:33][CH:34]=[CH:35][CH:36]=3)=[C:10]3[C:19]4[CH:18]=[C:17]([N:20]5[CH:24]=[C:23]([CH2:25][C@H:26]([OH:29])[CH2:27][OH:28])[N:22]=[N:21]5)[C:16]([O:30][CH3:31])=[CH:15][C:14]=4[CH2:13][CH2:12][N:11]3[C:7]=2[C:6]1=[O:41])([CH3:4])([CH3:3])[CH3:2].CC1(C)O[C@H](CC#C)CO1>>[C:1]([N:5]1[CH2:40][CH2:39][CH2:38][CH2:37][C:8]2[C:9]([C:32]3[S:33][CH:34]=[CH:35][CH:36]=3)=[C:10]3[C:19]4[CH:18]=[C:17]([N:20]5[CH:24]=[C:23]([CH2:25][C@@H:26]([OH:29])[CH2:27][OH:28])[N:22]=[N:21]5)[C:16]([O:30][CH3:31])=[CH:15][C:14]=4[CH2:13][CH2:12][N:11]3[C:7]=2[C:6]1=[O:41])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 50939112HCID 50939112, compoundHCID 87205187(4R)-2,2-Dimethyl-4-(2-propyn-1-yl)-1,3-dioxolane

Product 1

HCID 58124951HCID 58124951, compound

Procedure

The other enantiomer 20g was prepared analogous to 20f, starting from (R)-2,2-dimethyl-4-(prop-2-ynyl)-1,3-dioxolane.

Sources & evidence

ORD record
ord-6357fe684c4d4a1dbf9232b9bc216621
Source dataset
uspto-grants-2013_04
Patent number
US08431564B2

Reaction notes

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