HCID 53403158, compound → 6-Benzyloxy-1-methyl-5-oxo-1,5-dihydro-imidazo[1,2-a]pyrimidine-7-carboxylic acid [3-(3,4-dichloro-phenyl)-2-oxo-propyl]-amide

HRID 1971823Notes

Reaction equation

HRID 1971823 reaction equation
[CH2:1]([O:8][C:9]1[C:14](=[O:15])[N:13]2[CH:16]=[CH:17][N:18]([CH3:19])[C:12]2=[N:11][C:10]=1[C:20](O)=[O:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:24][CH2:25][C:26](=[O:36])[CH2:27][C:28]1[CH:33]=[CH:32][C:31]([Cl:34])=[C:30]([Cl:35])[CH:29]=1>>[Cl:35][C:30]1[CH:29]=[C:28]([CH2:27][C:26](=[O:36])[CH2:25][NH:24][C:20]([C:10]2[N:11]=[C:12]3[N:18]([CH3:19])[CH:17]=[CH:16][N:13]3[C:14](=[O:15])[C:9]=2[O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[O:21])[CH:33]=[CH:32][C:31]=1[Cl:34]

Participants

3

Reactant 2

HCID 53403158HCID 53403158, compoundHCID 581270346-Benzyloxy-1-methyl-5-oxo-1,5-dihydro-imidazo[1,2-a]pyrimidine-7-carboxylic acid

Product 1

HCID 581269776-Benzyloxy-1-methyl-5-oxo-1,5-dihydro-imidazo[1,2-a]pyrimidine-7-carboxylic acid [3-(3,4-dichloro-phenyl)-2-oxo-propyl]-amide

Procedure

Adapted from the procedure of example 5 using the product of example 9 and 1-amino-3-(3,4-dichloro-phenyl)-propan-2-one hydrochloride.

Sources & evidence

ORD record
ord-3c45267323824928a3f0627aa8bd93cb
Source dataset
uspto-grants-2013_04
Patent number
US08431581B2

Reaction notes

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