反应详情

To a solution of the product of example 86 (200 mg, 0.608 mmol) in MeOH (10 ml) was added Pd/C (20 mg, 10% Pd on carbon). The mixture was stirred at room temperature under H2 atmosphere overnight. The mixture was filtered and the filtrate was concentrated in vacuo. The resulting residue was purified by column chromatography (PE/EA=3/1) to give the desire product (150 mg, yield 74.5%).

1. filtrationThe mixture was filtered
2. concentrationthe filtrate was concentrated in vacuo
3. customThe resulting residue was purified by column chromatography (PE/EA=3/1)