HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 136331248, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 66922715 | HCID 66922715 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 136331248 | HCID 136331248 | 46% |
Reaction Steps
To a solution of the product of example 171 (38 mg, 0.06 mmol) in MeOH (5 ml) was added K2CO3 (20 mg, 0.14 mmol) and then the mixture was stirred at room temperature for 2 hours. The mixture was poured into water and extracted with dichloromethane. The organic layers were dried and concentrated. The resulting solids were collected and washed with cold MeOH (2-3 ml) to give the title compound (15 mg, yield 42%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431581B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-170beecd0467469998da8146d7803f46 |
| Source note | uspto-grants-2013_04 |