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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1971852Generated: November 2, 2026

Water → HCID 136331248, compound

https://huagongshe.com/reaction/1971852

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 66922715HCID 66922715—
SolventMethanolHCID 887—
ProductHCID 136331248HCID 13633124846%

Reaction Steps

To a solution of the product of example 171 (38 mg, 0.06 mmol) in MeOH (5 ml) was added K2CO3 (20 mg, 0.14 mmol) and then the mixture was stirred at room temperature for 2 hours. The mixture was poured into water and extracted with dichloromethane. The organic layers were dried and concentrated. The resulting solids were collected and washed with cold MeOH (2-3 ml) to give the title compound (15 mg, yield 42%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08431581B2
Source datasetuspto-grants-2013_04
ORD IDord-170beecd0467469998da8146d7803f46
Source noteuspto-grants-2013_04