HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → HCID 42635716, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 42635546 | HCID 42635546 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 42635716 | HCID 42635716 | 67% |
Reaction Steps
The alkylation of (II) by ethyl iodide is performed in boiling acetone with potassium carbonate as basic agent. 2-Ethyl-2-(1-trityl-1H-imidazole-4-yl)indan-1,3-dione (III) is formed in over 67% yield and easily isolated from the acetone solution by concentrating it and diluting with water. A high purity (III) is obtained after crystallization from methanol or ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431717B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-5daa0279bed94d9399c92028aa702d3c |
| Source note | uspto-grants-2013_04 |