Iodoethane → HCID 42635716, compound

Participants

Reaction Conditions

Reaction Steps

The intermediate 2-(1-Trityl-1H-imidazole-4-yl)indan-1,3-dione (79.4 g, 0.175 mol), potassium carbonate (72.5 g, 0.875 mol) and ethyl iodide (71 mL, 0.522 mol) were added to stirred acetone (1300 mL) in a 4-liter glass reactor, fitted with a mechanical stirrer, a thermometer and a reflux condenser. The reaction mixture was heated to reflux for 7 hours, then cooled to 20° C. and filtered. The inorganic residue on the filter was washed with acetone. The filtrate was concentrated in vacuo and poured into water.

Provenance & Evidence