HuagongsheHuagongshe Chemistry Print Report · For research reference only
NADPH → HCID 70655292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | NADPH | HCID 5884 | — |
| Reactant | HCID 66582843 | HCID 66582843 | — |
| Product | HCID 70655292 | HCID 70655292 | — |
Reaction Steps
(1S)-1-cyclopropyl-2,2,2-trifluoro-1-(4-(4-(phenylsulfonyl)-1-piperazinyl)phenyl)ethanol. 1H NMR (400 MHz, CD3OD) δ 7.88-7.78 (m, 2H), 7.74-7.57 (m, 3H), 7.48 (s, 2H), 6.96-6.83 (m, 2H), 3.28-3.23 (m, 4H), 3.18-3.05 (m, 4H), 1.61-1.48 (m, 1H), 0.76-0.63 (m, 1H), 0.58-0.46 (m, 1H), 0.44-0.34 (m, 1H), 0.30-0.20 (m, 1H). m/z (ESI, +ve ion) 441.0 (M+H)+. GK-GKRP EC50 (NADPH-coupled)=2.62 μM; GK-GKRP EC50 (LC MS/MS)=2.77 μM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431563B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-c1f71e989e5e4662821f7675267bfbad |
| Source note | uspto-grants-2013_04 |