HuagongsheHuagongshe Chemistry Print Report · For research reference only
NADPH → HCID 70655625, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | NADPH | HCID 5884 | — |
| Reactant | HCID 66582385 | HCID 66582385 | — |
| Product | HCID 70655625 | HCID 70655625 | — |
Reaction Steps
(2R)-2-(6-(3-chloro-4-(phenylsulfonyl)phenyl)-3-pyridinyl)-1,1,1-trifluoro-2-propanol. 1H NMR (400 MHz, CD3OD) δ 8.95-8.88 (m, 1H), 8.46 (d, J=8.0 Hz, 1H), 8.31-8.21 (m, 2H), 8.19-8.11 (m, 1H), 8.06-7.95 (m, 3H), 7.74-7.66 (m, 1H), 7.62 (s, 2H), 1.81 (s, 3H). m/z (ESI, +ve ion) 441.8 (M+H)+. GK-GKRP EC50 (NADPH-coupled)=3.75 μM; GK-GKRP EC50 (LC MS/MS)=3.57 μM.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431563B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-b869ab669d074a6e86875548e6371a63 |
| Source note | uspto-grants-2013_04 |