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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 197254Generated: October 30, 2026

1,2-Dichloroethane → Benzyl 2-(cis-4-hydroxycyclohexyl)-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylate

https://huagongshe.com/reaction/197254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantHydrochloric AcidHCID 313—
ReactantSodium ionHCID 923—
ReactantTriethylamineHCID 8471—
Reactant4-AminocyclohexanolHCID 81293—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant1-Benzyl 3-ethyl 3-(2-oxoethyl)piperidine-1,3-dicarboxylateHCID 59868916—
ProductBenzyl 2-(cis-4-hydroxycyclohexyl)-1-oxo-2,7-diazaspiro[4.5]decane-7-carboxylateHCID 57453748—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-caffd9abf59a440a852543a8f513310b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)