Hydrochloric Acid → ethyl (2S)-2-amino-3-(3-methoxyphenyl)propanoate

Participants

Reaction Steps

To a 100-mL round-bottomed flask was added ethyl N-(diphenylmethylidene)-3-methoxyphenylalaninate (912 mg, 2.35 mmol), 5 M hydrochloric acid (0.471 mL, 2.35 mmol) and THF (20 mL). The reaction mixture was stirred at room temperature for 1 h. The solvent was removed in vacuo to give the crude product, ethyl 3-methoxyphenylalaninate which was used without further purification.

Provenance & Evidence