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HRID1972625

反应详情

EQUATION

反应方程式

HRID 1972625 的结构方程式

REACTANTS

反应物

2
结构：CCC(C)S(=O)(=O)Cl
HCID2757336

butane-2-sulfonyl chloride

C4H9ClO2S

结构：CC(C)S(=O)(=O)NC[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1
HCID56932936

未命名化合物

PRODUCTS

生成物

1
结构：CCC(C)S(=O)(=O)NC[C@H]1CN(S(=O)(=O)c2cccs2)CCN1c1ccc(C(C)(O)C(F)(F)F)cc1
HCID66582308

未命名化合物

PROCEDURE

实验过程

According to the procedure for Example 237, the reaction of 2-(4-((2S)-2-(aminomethyl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)phenyl)-1,1,1-trifluoro-2-propanol (Example 237, Step 2) and butane-2-sulfonyl chloride (Sigma-Aldrich, St. Louis, Mo.) gave N-(((2S)-4-(2-thiophenylsulfonyl)-1-(4-(2,2,2-trifluoro-1-hydroxy-1-methylethyl)phenyl)-2-piperazinyl)methyl)-2-butanesulfonamide as a mixture of 4 compounds.