Sodium Sulfite → Sodium 4-bromo-3-methylbenzenesulfinate

Participants

Reaction Conditions

Reaction Steps

To a 100-mL round-bottomed flask was added sodium bicarbonate (1.18 g, 14 mmol, Sigma-Aldrich, St. Louis, Mo.), sodium sulfite (1.77 g, 14 mmol, Sigma-Aldrich, St. Louis, Mo.) and water (15 mL). The reaction mixture was heated at 80° C. and 4-bromo-3-methylbenzenesulfonyl chloride (3.15 g, 11.69 mmol, Sigma-Aldrich, St. Louis, Mo.) was added portion-wise. When the addition was completed the reaction mixture was heated at 90° C. for 3 h and allowed to cool to room temperature. The solvent was partially removed under vacuum and the white precipitate obtained was filtered and dried in vacuo to provide sodium 4-bromo-3-methylbenzenesulfinate (2.94 g) that was used without further purification.

Provenance & Evidence