2-benzyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-Indazole → HCID 58529607, compound

HRID 1972749Notes

Reaction equation

HRID 1972749 reaction equation
[CH2:1]([N:8]1[CH:16]=[C:15]2[C:10]([CH:11]=[C:12]([B:17]3[O:21][C:20]([CH3:23])([CH3:22])[C:19]([CH3:25])([CH3:24])[O:18]3)[CH:13]=[CH:14]2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([N:33]1C(N)=C2C(C=C(Br)C=C2)=N1)C1C=CC=CC=1>>[CH2:1]([N:8]1[C:16]([NH2:33])=[C:15]2[C:10]([CH:11]=[C:12]([B:17]3[O:18][C:19]([CH3:25])([CH3:24])[C:20]([CH3:23])([CH3:22])[O:21]3)[CH:13]=[CH:14]2)=[N:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 585293132-benzyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-Indazole2×HCID 58529737HCID 58529737, compound

Product 1

HCID 58529607HCID 58529607, compound

Procedure

This compound was prepared in a manner similar to the procedure described for the preparation of 2-benzyl-6-(4,4,5,5-tetramethyl-{1,3,2]dioxaborolan-2-yl)-2H-indazole (Intermediate C, step 2), using 2-benzyl-6-bromo-2H-indazol-3-ylamine in place of 2-benzyl-6-bromo-2H-indazole. 1H-NMR (300 MHz, CD2Cl2) 7.95 (s, 1H), 7.44 (dd, 1H), 7.63 to 7.29 (m, 3H), 7.29 to 7.17 (m, 3H), 5.51 (s, 2H), 3.88 (broad s, 2H), 1.36 (s, 12H).

Workup

  1. customThis compound was prepared in a manner similar to the procedure

Sources & evidence

ORD record
ord-194782c2953347aeaec17377e458b253
Source dataset
uspto-grants-2013_04
Patent number
US08431695B2

Reaction notes

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