2-benzyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-Indazole → HCID 58529933, compound

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Reaction Steps

Using a procedure similar to that of Example 4 with 5-bromo-7-(2-chloro-pyridin-4-yl)-pyrrolo[2,1-f][1,2,4]triazin-4-ylamine and 2-benzyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxa-borolan-2-yl)-2H-indazole as starting materials, 60 mg (28%) of the desired product was isolated. 1H NMR (300 MHz, DMSO-d6) δ 8.60 (s, 1 H), 8.5 (d, 2 H), 8.0 (m, 2 H), 7.90 (d, 1 H), 7.70 (s, 1 H), 7.60-7.40 (m, 3 H), 7.25-7.15 (m, 4 H), 7.20 (s, 1 H), 5.70 (s, 2 H); ES-MS m/z 45224 [M+H]+, HPLC RT (min) 3.33.

Provenance & Evidence