HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → N'-(propan-2-ylidene)(tert-butoxy)carbohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | tert-Butyl carbazate | HCID 70091 | — |
| Catalyst | Acetic Acid | HCID 176 | — |
| Product | N'-(propan-2-ylidene)(tert-butoxy)carbohydrazide | HCID 11435207 | 98% |
Reaction Steps
To a solution of tert-butyl hydrazinecarboxylate (25.1 g, 0.190 mol) in acetone (185 mL) was added the magnesium sulfate (6 g) and 12 drops acetic acid. The mixture was heated to reflux for 2.5 h and cooled to rt and filtered. The filtrate was concentrated to give an off-white solid (32 g, 98%) (used in the next step without further purification). LC-MS [M+H]+=172.9, RT=2.11 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08431695B2 |
| Source dataset | uspto-grants-2013_04 |
| ORD ID | ord-80945dec405248e7831b8c42383046e7 |
| Source note | uspto-grants-2013_04 |